Academician Valeriu Rudic, the inventor of BioR®.

In the 1990s, the academician Valeriu Rudic founded a new scientific direction in the sphere of fundamental and applied biotechnological research. The scientist aimed to elaborate new methods of directed synthesis of biologically active substances with sanogene effects and of producing in controlled conditions of Arthrospira (Spirulina platensis) cyanobacteria biomass with a forecasted biochemical content. The invention of new methods of extraction and separation from Spirulina biomass, in combination with biochemical methods and procedures of fractionation of bioactive principles and their purification, has culminated in elaboration and implementation of integrated techological schemes, of a new biological substance with a complex structure and great impact, BihoR®. The profile and therapeutic compliance of BihoR® are determined by the complexity of the mechanisms and their effects (antioxidant, cytoprotective, anti-inflammatory, immunomodulatory, anti-viral, hepatoprotective, normolipidemic, antiatherogen action) confirmed by multiple biomedical, clinical and toxicology researches.

The contribution of scientist Valeriu Rudic, to the evolution of biotechnological research and diversification of medical practice is incontestable. By applying modern pharmacological techniques, based on BioR® , a series of new pharmaceutical products were elaborated, registered and included in multiple prophylaxis and treatment schemes: BioR® solution for injection 0.5% and BioR® capsules 5.0 mg (liver and pancreas pathologies), BioR® suppositories 10.0 mg (dysfunctions of the man’s reproductive system), BioR® capsules 5.0 mg (gynecological diseases), BioR® gel 1%, Levobior unguent and Angenol gel (oro-maxillofacial pathologies).

Recently, based on BioR® , a new hygienic products have been developed, registered and introduced in fabrication: BioR® nasal spray (for nasal cavity hygiene), BioR® oromucosal spray (for oro-pharyngeal cavity hygiene). Also, in the Republic of Moldova and Romania, new nutritional supplements Imunobior® (which contains sulfated polysaccharides and incorporated zinc) and Aterobior® (containing phospholipids and incorporated selenium) have been registered. These nutritional supliments have antioxidant, depurative effect, regulating some metabolic functions and normalizing the protective function of the body. The complexity of the action mechanisms, high accesibility and direct involvement in the deregulated metabolic processes, the reduction or absence of adverse effects, inoffencive and non-toxic origin, are criteria that ensure the promotion of the new generation of therapeutic remedies. They are competitive in the prophylaxis, treatment and combating of pathological states of the organism. Biological active compounds from various unconventional sources, including cyanobacteria and microalgae, is the subject of numerous studies with extensive research area: from medical and pharmaceutical biotechnology to experimental and clinical medicine.

Academician Gheorghe DUCA